SCIENCE
Research is where every Stellar formula starts.
Stellar is built around a single discipline: published clinical research drives the formula, not the other way around. This page documents the principles that govern how research becomes product.
FOUR OPERATING PRINCIPLES
How research becomes formula.
The science discipline isn't a marketing claim. It's an operating method that gates what ships.
01 · PRIMARY
Peer-reviewed first.
We anchor to peer-reviewed clinical literature over secondary sources. Mechanism-of-action research is supporting context, not substitute evidence.
02 · DOSED
Dose is research-anchored.
Each ingredient's dose maps to the dose range studied in published clinical research — not to arbitrary RDV targets.
03 · OPTIMIZED
AI screens combinations against the literature.
Models cross-reference candidate combinations against published data — flagging conflicts, redundancies, and dose-rationale gaps before manufacturing.
04 · PUBLISHED
Per-claim source list.
Each structure/function statement on a Stellar product maps to a published reference. The list is inspectable rather than walled-off.
ON AI-FORMULATION
WHAT 'AI-FORMULATED' MEANS HERE
AI screens published research. It does not invent doses.
'AI-formulated' is one of the more abused phrases in the supplement category. At Stellar it has a specific operating meaning: large-corpus models read across published clinical research to surface ingredient combinations, dose-response relationships, and interaction signals that a human researcher would take materially longer to map.
It is a literature-screening discipline — not a generation discipline.
Every dose that ships is justified against the same published source set the AI consulted. The methodology is reviewed by evidence review, the lab issues the COA, and the formula is auditable end-to-end. AI accelerates the literature pass; it does not bypass it.
SHILAJIT MATRIX+
Every active. Every dose. The reasoning.
Tap any active to see why we chose the dose, the mechanism, and the studies the choice is anchored to. Amounts are per 2-capsule serving.
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01 Shilajit fulvic complex 500mg
Why this dose
500 mg is the higher of the two doses in the human strength RCT (Keller 2019), the dose at which an effect was reported; that extract was standardized differently from ours. Our extract is standardized to 70% fulvic acid, verified per lot on the Certificate of Analysis.
Mechanism
Supports cellular energy production by contributing fulvic acid and dibenzo-α-pyrones implicated in CoQ10 transport.
Source(s)
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02 Urolithin A 250mg
Why this dose
250 mg is inside the studied 10–1,000 mg/day range; the muscle and mitochondrial-gene outcomes were reported at 500–1,000 mg/day. Stated plainly.
Mechanism
Activates mitophagy — the cell's recycling process for damaged mitochondria.
Source(s)
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03 Nicotinamide Riboside 150mg
Why this dose
Single doses of 100–1,000 mg raised the blood NAD+ metabolome dose-dependently; 150 mg is an NAD+-precursor amount inside that tested range, within a combined formula.
Mechanism
Serves as a precursor for NAD+ — a cofactor required by sirtuins and mitochondrial enzymes.
Source(s)
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04 CoQ10 (ubiquinol) 200mg
Why this dose
200 mg per day of the reduced ubiquinol form sits in the human bioenergetic dose range; ubiquinol is selected for higher bioavailability than ubiquinone.
Mechanism
Electron transport in the mitochondrial respiratory chain.
Source(s)
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05 PQQ 20mg
Why this dose
Held at the dose where a 2013 human study observed inflammation and mitochondrial-related metabolism shifts.
Mechanism
Cofactor implicated in mitochondrial biogenesis; reduces mitochondrial oxidative stress in vitro.
Source(s)
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06 Astaxanthin 12mg
Why this dose
Dosed at 12 mg, toward the upper end of the 2–12 mg/day range used in human antioxidant trials; the exact per-lot amount is disclosed on the Certificate of Analysis.
Mechanism
Lipid-phase antioxidant with reported activity in cell membranes and mitochondrial inner membrane.
Source(s)
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07 Alpha-Lipoic Acid (R-isomer) 125mg
Why this dose
Human ALA studies commonly use higher amounts (roughly 200–2,400 mg/day; PK studies used 500–600 mg). 125 mg is a supporting cofactor amount inside a combined formula; we do not claim it reproduces those higher-dose results.
Mechanism
Cofactor for mitochondrial enzymes; recycles other antioxidants in vivo.
Source(s)
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08 Black pepper extract (BioPerine®) 10mg
Why this dose
Dosed at 10 mg (standardized to 95% piperine), the amount used in absorption-enhancement studies for co-administered actives; the exact per-lot amount is disclosed on the Certificate of Analysis.
Mechanism
Inhibits intestinal glucuronidation; can increase bioavailability of co-administered ingredients.
Source(s)
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09 Apigenin 15mg
Why this dose
Included for its role in the NAD+ pathway. In cell and animal studies apigenin inhibits CD38, the main NAD+-consuming enzyme, which is why it sits beside nicotinamide riboside; the evidence is preclinical and is presented as rationale, not an outcome.
Mechanism
A chamomile/parsley flavone studied as a CD38 inhibitor in preclinical models.
Source(s)
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10 Spermidine (wheat germ) 5mg
Why this dose
A polyamine studied alongside urolithin A for complementary autophagy and mitophagy roles. Stated plainly: controlled human pharmacokinetic work found 15 mg/day did not raise plasma spermidine and 40 mg/day was well tolerated; our amount is below both. Contains wheat.
Mechanism
Induces autophagy — the cell's recycling system.
Source(s)
PEER-REVIEWED REFERENCES
Studies our formulations are anchored to.
A non-exhaustive list of the published research that informed dose ranges, ingredient choices, and combinations across the Stellar line. Each entry links out to PubMed or the source journal.
3 of 3 references
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01
View on PubMed →
MITOCHONDRIAL RENEWAL
The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans.
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02
View on PubMed →
NAD+ METABOLISM
Nicotinamide riboside is uniquely and orally bioavailable in mice and humans.
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03
View on PubMed →
MITOCHONDRIAL FUNCTION
Dietary pyrroloquinoline quinone (PQQ) alters indicators of inflammation and mitochondrial-related metabolism in human subjects.
No references match those filters.
Citations describe the topic of each study, not Stellar product claims. Stellar formulas are dietary supplements; structure/function statements have not been evaluated by the FDA. See the full DSHEA disclaimer in the footer.
GO DEEPER
Where the science lives on this site.
METHODOLOGY
How we formulate.
The literature review, AI-optimization, dose justification, and pre-manufacturing audit pipeline.
Read methodology →RESEARCH LIBRARY
Research library.
Ingredient deep-dives, methodology essays, and the COA library — organized for the documentation-reader.
Open library →VERIFICATION
Verification chain.
Third-party lab, per-batch assay set, and the COA review process that gates every release.
Read verification →READ THE WORK
The methodology is inspectable.
Read the full methodology framework, browse research by ingredient, or jump straight to a formula.